Immunophenotypic , and Immunogenotypic Analyses of Immunoblastic Lymphadenopathy - Like T Cell Lymphoma

نویسندگان

  • Kensei Tobinai
  • Keisuke Minato
  • Tomoko Ohtsu
  • Kiyoshi Mukai
  • Yoshitoyo Kagami
  • Masanao Miwa
  • Masanori Shimoyama
چکیده

Immunoblastic lymphadenopathy (lBL)-like T-cell lymphoma is a distinct peripheral T-cell lymphoma. which closely resembles angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) and/or IBL. but is characterized by focal or sheet-like proliferation of immunoblasts and pale cells of T-cell nature. In this report. 36 patients with IBI-like T-cell lymphoma were analyzed. The disease is clinically characterized by generalized lymph node swelling. hepatosplenomegaly. fever. skin rash. polyclonal hypergammaglobulinemia. marked male predominance. predilection for the elderly. and poor prognosis. There was no association with human T-cell leukemia virus type I or human immunodeficiency virus. IBL-like T-cell lymphoma may be divided into two categories (CD4+ type and CD8+

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تاریخ انتشار 2005